As production systems are being connected to the internet, production plant are automatically sub-ject to the increasing threat of cyber-attacks. Thus, IT-security solutions that guard connected in-dustrial production systems and prevent unauthorized access, manipulation or misuse. In IUNO we identify and analyze threats and risks for the smart factory, develop protective measure and imple-ment them exemplarily. The goal is to develop universally applicable solutions to the challenges that occur regarding the IT-security in industrial production systems. These solutions shall be primarily applicable to small and medium-sized enterprises, serving as a blueprint for secure Industry 4.0.